Evaluation of Anti Tumor Activity of Curcuma Amda Roxb. Rhizome

نویسندگان

  • Amit Upadhyay
  • Ravi Kant Sharma
  • Gurdeep Singh
  • A. K. Jain
چکیده

Aqueous and alcoholic extracts of curcuma amda roxb. rhizomes have been evaluated for its anti tumour activity in Swiss albino mice. Alcoholic extract exhibited more potent anti tumour activity than aqueous extract. In-vitro cytotoxicity studies were confirmed by brine shrimp bioassay method. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour induced mice after treatment with both of the extracts in ehrlich ascites carcinoma (EAC) model. The hematological parameters were also corrected by aqueous and ethanolic extracts in tumour induced mice. These observations are suggestive of the anti tumour effect of aqueous and alcoholic extracts of Curcuma amda Roxb. rhizomes in ehrlich ascites carcinoma. Keywordsanti tumour activity, brine shrimp bioassay, curcuma amda roxb., ehrlich ascites carcinoma. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _****_ _ _ _ _ _ _ _ _ _ _ _ __

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تاریخ انتشار 2013